
π SIRT6 Longevity Platform: Accelerated Development Strategy π
Sirtuin-6 (SIRT6) is a NADβΊ-dependent enzyme linked to genomic stability and aging. Studies suggest that SIRT6 overexpression or activation enhances DNA repair and metabolic regulation, conferring anti-aging effects [Nature]. These properties make SIRT6 a prime longevity target for a fast-tracked R&D pipeline. Below is an accelerated development framework that integrates:
β Optimized DNA design for maximal SIRT6 expression
β Diverse expression systems (E. coli, yeast, mammalian, cell-free)
β CRISPR activation for endogenous SIRT6 upregulation
β High-throughput protein production & purification
β Regulatory and market path analysis
β Bioelectric module for future integration
By running parallel experimental workflows and leveraging automation + AI-driven insights, we aim to compress R&D timelines for a viable SIRT6-based intervention.